ASSOCIATION OF HYPERTHYROIDISM AND BLOOD GLUCOSE LEVELS IN PATIENTS ATTENDING ELOBIED HOSPITAL IN WESTERN SUDAN

Maysoon Alzubeir Hassaan, Badreldin Elsonni Abdalla, Majdolin Mohammed Eltyeb, Hani Yousif Zaki, Ahmed Abdalla Agabeldour

Abstract


Objective: The objective of this study was to examine the effect of hyperthyroidism on blood glucose levels.

Materials and methods: Comparative descriptive study was done in twenty four patients with hyperthyroidism referred to Elobied hospital during May –July 2008, their ages ranged from 14 to 65 years; thirty three healthy volunteers with matching age and sex were included. Data collected through, clinical evaluation form, questionnaire, and laboratory investigations. Serum concentrations of total triiodothyronine (TT3), total tetariodothyronine (TT4) and thyroid stimulating hormone (TSH) were measured by enzyme linked immune sorbent assay (ELISA) and blood glucose concentrations (BGC) were measured by colorimetric method.

Results: The patients showed a concentration of TT4 more than 11.6µg/dl (higher than normal upper limit). The prevalence of glucose intolerance in hyperthyroid patients was 29.17% (n= 7). The glucose intolerance was significantly correlated with serum TT4 levels (p=0.006, r=0.252).

Conclusion: Glucose intolerance is associated with high TT4 levels in hyperthyroid patients.

Key words: Thyroid, goiter, hyperthyroidism, glucose tolerance, Western Sudan.



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