Assessment of Serum Levels of Aminotransferse and Alkaline phosphatase Activity among Chronic Renal Failure with Hemodialysis
Abstract
Abstract
Background: The serum enzymes of patients with end-stage renal disease (ESRD) are commonly abnormal .This is due in part to the absence of renal excretion and to the frequent presence of multiple co morbid conditions. Objective: we aimed to assess the serum liver enzymes alkaline phosphatase (ALP),alanine aminotransferase (ALT), aspartate aminotransferase (AST) in Sudanese patients with chronic renal failure. Materials and Methods: An analytical case control hospital based study. The conducted was in Ahmed Gasim Hospital at dialysis session, Khartoum Bahry, Khartoum state and carried out during from February to August 2019. A total of 100 subjects enrolled in the study, 60 patients with chronic renal failure as case group and 40 apparently healthy subjects as control group. The serum liver enzymes were estimated using spectrophotometer (auto biochemical analyzer).The data was analyzed using SPSS program version (16).Results: Our result shows that, the serum ALP was significantly increase in chronic renal failure compare to control group (p = 0.001), while serum ALT and AST were significantly decrease in chronic renal failure compare to control group respectively (p=0.000). Their negative association between age and serum ALT and AST respectively (r= -0.516, p = 0.000), (r= -0.489, p = 0.000), and also negative association between duration of disease/years and serum ALT and AST respectively (r= -0.333, p = 0.009), (r= -0.290, p = 0.025).Conclusion: Our study concluded that, The serum ALP was highly higher while the serum ALT and AST were a highly lower in chronic renal failure. And also the serum ALT and AST were negative association with age and duration of disease.
References
References
1. Levey, A.S. ; Eckardt, K.U. and Tsukamoto, Y. ( 2005). Definition and classification of chronic kidney disease: a position statement from Kidney Disease:Improving Global Outcomes (KDIGO). Kidney Int.;67: 2089.
2. Abdelsamee E. M. Elamin,, Nagah A. A. Mohammed, Gad Allah Modawe. Aetiology of End-Stage Renal Disease among adult Sudanese patient. Sudan JMS Vol. 7, No.4. December 2012.
3. Elsharif ME, Elsharif EG. Causes of end-stagerenal disease in Sudan: A single centre experience.Saudi J Kidney Dis Transpl. 2011; 22: 373-376.
4. Musher Ismail Salih Kakey and Kamaran Kaiani Abdoulrahman. Estimation of Liver Parameters and Oxidative Stress in Chronic Renal Failure Patients on Hemodialysis in ErbilGovernorate. AIP Conference Proceedings 1888, 020029 (2017); https://doi.org/10.1063/1.5004306. Published Online: 21 September 2017.
5. Lomashvili, K.A., Garg, P., Narisawa, S., Millan, J.L. and O'Neill, W.C., Kidney international, 73 (9), 10241030(2008).
6. Fabrizi, F., Lunghi, G., Finazzi, S., Colucci, P., Pagano, A., Ponticelli, C. and Locatelli, F., American journal of kidney diseases, 38(5), 1009-1015 (2001).
7. Lopes, E.P., Sette, L.H.B., Sette, J.B.C., Luna, C.F., Andrade, A.M., Moraes, M., Sette, P.C., Menezes, R.,Cavalcanti, R.L. and Conceição, S.C., Clinics, 64 (10), 941-945 (2009).
8. Riyadh Hussein Wally. Effects of Chronic Kidney Disease on Some Liver Enzymes Activity before and After Dialysis. Journal of primary education.22 (96), 2016. 89-94.
9. Steel, R.G. and Torrie, J.H. Principle and procedure of statistics a biometrical approach1984.2nd., Mc.Graw-Hill,Inc.,Singapore.
10 . Wolf, P.L. ; Williams, D.; Coplon, N. and Coulson A.S. Lowaspartate transaminase activity in serum of patients undergoing chronic hemodialysis. Clin Chem . 2008. 18:567..
11. Olut, A.I. ; Ozsakarya, F.and Dilek, M. Seroprevalence ofhepatitis C virus infection and evaluation of serum aminotransferaselevels among haemodialysis patients in Izmir, Turkey. J Int. Med.Res.2005 ;33(6):641–6.
12. Trevizoli, J.E.; de Paula, ; Menezes, R. ; Ribeiro Velasco, L.F. ;
Amorim, R. ; de Carvalho, M.B. and Mendes L.S., et al. (). Hepatitis C is less aggressive in hemodialysis patients than in nonuremic patients. Clin. J. Am. Soc. Nephrol; 2008.3:1385-90
13. Fabrizi, F. ; Lunghi, G. ; Finazzi, S. ; Colucci, P. ; Pagano, A. andPonticelli, C. et al, Decreased serum aminotransferase activityin patients with chronic renal failure: impact on the detection of viral hepatitis. Am. J. Kidney Dis. ; 2001.38:1009–15.
14. Torres, P.U. Bone alkaline phosphatase isoforms in chronicrenal failure. Kidney Int.; 2002. 61:1178-9.
15.Regidor, D.L. ; Kovesdy, C.P. ; Mehrotra, R. ; Rambod, M. ;Jing, J.and McAllister C.J. et al. Serum alkaline phosphatase predictsmortality among maintenance hemodialysis patients. J. Am. Soc.Nephrol; 2004.19:2193-203.
16. Al-Wakeel J, Mailk GH, Al-Mohaya S, Mitwalli A, Baroudi F, El Gamal
H, et al. Liver disease in dialysis patients with antibodies to hepatitis C
virus. Nephrol Dial Transplant. 1996;11:2265-8.
17. Yuki N, Ishida H, Inoue T, Tabata T, Matsushita Y, Sasaki Y, et al.
Reappraisal of biochemical hepatitis C activity in hemodialysis patients.
J Clin Gastroenterol. 2000;30:187-94, http://dx.doi.org/10.1097/
00004836-200003000-00012.
18. lopes EP, Sette LH, Sette JB, Luna CF, Andrade AM, Moraes M, et al.
Serum alanine aminotransferase levels, hematocrit rate and body weight
correlations before and after hemodialysis session. Clinics (Sao Paulo).2009;64:941-5.
19.Trevizoli JE, Menezes R, Velasco LF, Amorim R, de Carvalho MB,
Mendes LS, et al. Hepatitis C is less aggressive in hemodialysis patients
than in nonuremic patients. Clin J Am Soc Nephrol. 2008;3:1385-90,
http://dx.doi.org/10.2215/CJN.01330308.
20. Cotler SJ, Diaz G, Gundlapalli S, Jakate S, Chawla A, Mital D, et al.
Characteristics of hepatitis C in renal transplant candidates. J Clin
Gastroenterol. 2002;35:191-5, http://dx.doi.org/10.1097/00004836-2002
08000-00013.
21. Ray L, Nanda SK, Chatterjee A, Sarangi R, Ganguly S.A comparative study of serum aminotransferases in chronic kidney diseasewith and without end-stage renal disease: Need for new reference ranges. Int J App Basic Med Res 2015;5:31-5.
References
1. Levey, A.S. ; Eckardt, K.U. and Tsukamoto, Y. ( 2005). Definition and classification of chronic kidney disease: a position statement from Kidney Disease:Improving Global Outcomes (KDIGO). Kidney Int.;67: 2089.
2. Abdelsamee E. M. Elamin,, Nagah A. A. Mohammed, Gad Allah Modawe. Aetiology of End-Stage Renal Disease among adult Sudanese patient. Sudan JMS Vol. 7, No.4. December 2012.
3. Elsharif ME, Elsharif EG. Causes of end-stagerenal disease in Sudan: A single centre experience.Saudi J Kidney Dis Transpl. 2011; 22: 373-376.
4. Musher Ismail Salih Kakey and Kamaran Kaiani Abdoulrahman. Estimation of Liver Parameters and Oxidative Stress in Chronic Renal Failure Patients on Hemodialysis in ErbilGovernorate. AIP Conference Proceedings 1888, 020029 (2017); https://doi.org/10.1063/1.5004306. Published Online: 21 September 2017.
5. Lomashvili, K.A., Garg, P., Narisawa, S., Millan, J.L. and O'Neill, W.C., Kidney international, 73 (9), 10241030(2008).
6. Fabrizi, F., Lunghi, G., Finazzi, S., Colucci, P., Pagano, A., Ponticelli, C. and Locatelli, F., American journal of kidney diseases, 38(5), 1009-1015 (2001).
7. Lopes, E.P., Sette, L.H.B., Sette, J.B.C., Luna, C.F., Andrade, A.M., Moraes, M., Sette, P.C., Menezes, R.,Cavalcanti, R.L. and Conceição, S.C., Clinics, 64 (10), 941-945 (2009).
8. Riyadh Hussein Wally. Effects of Chronic Kidney Disease on Some Liver Enzymes Activity before and After Dialysis. Journal of primary education.22 (96), 2016. 89-94.
9. Steel, R.G. and Torrie, J.H. Principle and procedure of statistics a biometrical approach1984.2nd., Mc.Graw-Hill,Inc.,Singapore.
10 . Wolf, P.L. ; Williams, D.; Coplon, N. and Coulson A.S. Lowaspartate transaminase activity in serum of patients undergoing chronic hemodialysis. Clin Chem . 2008. 18:567..
11. Olut, A.I. ; Ozsakarya, F.and Dilek, M. Seroprevalence ofhepatitis C virus infection and evaluation of serum aminotransferaselevels among haemodialysis patients in Izmir, Turkey. J Int. Med.Res.2005 ;33(6):641–6.
12. Trevizoli, J.E.; de Paula, ; Menezes, R. ; Ribeiro Velasco, L.F. ;
Amorim, R. ; de Carvalho, M.B. and Mendes L.S., et al. (). Hepatitis C is less aggressive in hemodialysis patients than in nonuremic patients. Clin. J. Am. Soc. Nephrol; 2008.3:1385-90
13. Fabrizi, F. ; Lunghi, G. ; Finazzi, S. ; Colucci, P. ; Pagano, A. andPonticelli, C. et al, Decreased serum aminotransferase activityin patients with chronic renal failure: impact on the detection of viral hepatitis. Am. J. Kidney Dis. ; 2001.38:1009–15.
14. Torres, P.U. Bone alkaline phosphatase isoforms in chronicrenal failure. Kidney Int.; 2002. 61:1178-9.
15.Regidor, D.L. ; Kovesdy, C.P. ; Mehrotra, R. ; Rambod, M. ;Jing, J.and McAllister C.J. et al. Serum alkaline phosphatase predictsmortality among maintenance hemodialysis patients. J. Am. Soc.Nephrol; 2004.19:2193-203.
16. Al-Wakeel J, Mailk GH, Al-Mohaya S, Mitwalli A, Baroudi F, El Gamal
H, et al. Liver disease in dialysis patients with antibodies to hepatitis C
virus. Nephrol Dial Transplant. 1996;11:2265-8.
17. Yuki N, Ishida H, Inoue T, Tabata T, Matsushita Y, Sasaki Y, et al.
Reappraisal of biochemical hepatitis C activity in hemodialysis patients.
J Clin Gastroenterol. 2000;30:187-94, http://dx.doi.org/10.1097/
00004836-200003000-00012.
18. lopes EP, Sette LH, Sette JB, Luna CF, Andrade AM, Moraes M, et al.
Serum alanine aminotransferase levels, hematocrit rate and body weight
correlations before and after hemodialysis session. Clinics (Sao Paulo).2009;64:941-5.
19.Trevizoli JE, Menezes R, Velasco LF, Amorim R, de Carvalho MB,
Mendes LS, et al. Hepatitis C is less aggressive in hemodialysis patients
than in nonuremic patients. Clin J Am Soc Nephrol. 2008;3:1385-90,
http://dx.doi.org/10.2215/CJN.01330308.
20. Cotler SJ, Diaz G, Gundlapalli S, Jakate S, Chawla A, Mital D, et al.
Characteristics of hepatitis C in renal transplant candidates. J Clin
Gastroenterol. 2002;35:191-5, http://dx.doi.org/10.1097/00004836-2002
08000-00013.
21. Ray L, Nanda SK, Chatterjee A, Sarangi R, Ganguly S.A comparative study of serum aminotransferases in chronic kidney diseasewith and without end-stage renal disease: Need for new reference ranges. Int J App Basic Med Res 2015;5:31-5.
References
1. Levey, A.S. ; Eckardt, K.U. and Tsukamoto, Y. ( 2005). Definition and classification of chronic kidney disease: a position statement from Kidney Disease:Improving Global Outcomes (KDIGO). Kidney Int.;67: 2089.
2. Abdelsamee E. M. Elamin,, Nagah A. A. Mohammed, Gad Allah Modawe. Aetiology of End-Stage Renal Disease among adult Sudanese patient. Sudan JMS Vol. 7, No.4. December 2012.
3. Elsharif ME, Elsharif EG. Causes of end-stagerenal disease in Sudan: A single centre experience.Saudi J Kidney Dis Transpl. 2011; 22: 373-376.
4. Musher Ismail Salih Kakey and Kamaran Kaiani Abdoulrahman. Estimation of Liver Parameters and Oxidative Stress in Chronic Renal Failure Patients on Hemodialysis in ErbilGovernorate. AIP Conference Proceedings 1888, 020029 (2017); https://doi.org/10.1063/1.5004306. Published Online: 21 September 2017.
5. Lomashvili, K.A., Garg, P., Narisawa, S., Millan, J.L. and O'Neill, W.C., Kidney international, 73 (9), 10241030(2008).
6. Fabrizi, F., Lunghi, G., Finazzi, S., Colucci, P., Pagano, A., Ponticelli, C. and Locatelli, F., American journal of kidney diseases, 38(5), 1009-1015 (2001).
7. Lopes, E.P., Sette, L.H.B., Sette, J.B.C., Luna, C.F., Andrade, A.M., Moraes, M., Sette, P.C., Menezes, R.,Cavalcanti, R.L. and Conceição, S.C., Clinics, 64 (10), 941-945 (2009).
8. Riyadh Hussein Wally. Effects of Chronic Kidney Disease on Some Liver Enzymes Activity before and After Dialysis. Journal of primary education.22 (96), 2016. 89-94.
9. Steel, R.G. and Torrie, J.H. Principle and procedure of statistics a biometrical approach1984.2nd., Mc.Graw-Hill,Inc.,Singapore.
10 . Wolf, P.L. ; Williams, D.; Coplon, N. and Coulson A.S. Lowaspartate transaminase activity in serum of patients undergoing chronic hemodialysis. Clin Chem . 2008. 18:567..
11. Olut, A.I. ; Ozsakarya, F.and Dilek, M. Seroprevalence ofhepatitis C virus infection and evaluation of serum aminotransferaselevels among haemodialysis patients in Izmir, Turkey. J Int. Med.Res.2005 ;33(6):641–6.
12. Trevizoli, J.E.; de Paula, ; Menezes, R. ; Ribeiro Velasco, L.F. ;
Amorim, R. ; de Carvalho, M.B. and Mendes L.S., et al. (). Hepatitis C is less aggressive in hemodialysis patients than in nonuremic patients. Clin. J. Am. Soc. Nephrol; 2008.3:1385-90
13. Fabrizi, F. ; Lunghi, G. ; Finazzi, S. ; Colucci, P. ; Pagano, A. andPonticelli, C. et al, Decreased serum aminotransferase activityin patients with chronic renal failure: impact on the detection of viral hepatitis. Am. J. Kidney Dis. ; 2001.38:1009–15.
14. Torres, P.U. Bone alkaline phosphatase isoforms in chronicrenal failure. Kidney Int.; 2002. 61:1178-9.
15.Regidor, D.L. ; Kovesdy, C.P. ; Mehrotra, R. ; Rambod, M. ;Jing, J.and McAllister C.J. et al. Serum alkaline phosphatase predictsmortality among maintenance hemodialysis patients. J. Am. Soc.Nephrol; 2004.19:2193-203.
16. Al-Wakeel J, Mailk GH, Al-Mohaya S, Mitwalli A, Baroudi F, El Gamal
H, et al. Liver disease in dialysis patients with antibodies to hepatitis C
virus. Nephrol Dial Transplant. 1996;11:2265-8.
17. Yuki N, Ishida H, Inoue T, Tabata T, Matsushita Y, Sasaki Y, et al.
Reappraisal of biochemical hepatitis C activity in hemodialysis patients.
J Clin Gastroenterol. 2000;30:187-94, http://dx.doi.org/10.1097/
00004836-200003000-00012.
18. lopes EP, Sette LH, Sette JB, Luna CF, Andrade AM, Moraes M, et al.
Serum alanine aminotransferase levels, hematocrit rate and body weight
correlations before and after hemodialysis session. Clinics (Sao Paulo).2009;64:941-5.
19.Trevizoli JE, Menezes R, Velasco LF, Amorim R, de Carvalho MB,
Mendes LS, et al. Hepatitis C is less aggressive in hemodialysis patients
than in nonuremic patients. Clin J Am Soc Nephrol. 2008;3:1385-90,
http://dx.doi.org/10.2215/CJN.01330308.
20. Cotler SJ, Diaz G, Gundlapalli S, Jakate S, Chawla A, Mital D, et al.
Characteristics of hepatitis C in renal transplant candidates. J Clin
Gastroenterol. 2002;35:191-5, http://dx.doi.org/10.1097/00004836-2002
08000-00013.
21. Ray L, Nanda SK, Chatterjee A, Sarangi R, Ganguly S.A comparative study of serum aminotransferases in chronic kidney diseasewith and without end-stage renal disease: Need for new reference ranges. Int J App Basic Med Res 2015;5:31-5.
1. Levey, A.S. ; Eckardt, K.U. and Tsukamoto, Y. ( 2005). Definition and classification of chronic kidney disease: a position statement from Kidney Disease:Improving Global Outcomes (KDIGO). Kidney Int.;67: 2089.
2. Abdelsamee E. M. Elamin,, Nagah A. A. Mohammed, Gad Allah Modawe. Aetiology of End-Stage Renal Disease among adult Sudanese patient. Sudan JMS Vol. 7, No.4. December 2012.
3. Elsharif ME, Elsharif EG. Causes of end-stagerenal disease in Sudan: A single centre experience.Saudi J Kidney Dis Transpl. 2011; 22: 373-376.
4. Musher Ismail Salih Kakey and Kamaran Kaiani Abdoulrahman. Estimation of Liver Parameters and Oxidative Stress in Chronic Renal Failure Patients on Hemodialysis in ErbilGovernorate. AIP Conference Proceedings 1888, 020029 (2017); https://doi.org/10.1063/1.5004306. Published Online: 21 September 2017.
5. Lomashvili, K.A., Garg, P., Narisawa, S., Millan, J.L. and O'Neill, W.C., Kidney international, 73 (9), 10241030(2008).
6. Fabrizi, F., Lunghi, G., Finazzi, S., Colucci, P., Pagano, A., Ponticelli, C. and Locatelli, F., American journal of kidney diseases, 38(5), 1009-1015 (2001).
7. Lopes, E.P., Sette, L.H.B., Sette, J.B.C., Luna, C.F., Andrade, A.M., Moraes, M., Sette, P.C., Menezes, R.,Cavalcanti, R.L. and Conceição, S.C., Clinics, 64 (10), 941-945 (2009).
8. Riyadh Hussein Wally. Effects of Chronic Kidney Disease on Some Liver Enzymes Activity before and After Dialysis. Journal of primary education.22 (96), 2016. 89-94.
9. Steel, R.G. and Torrie, J.H. Principle and procedure of statistics a biometrical approach1984.2nd., Mc.Graw-Hill,Inc.,Singapore.
10 . Wolf, P.L. ; Williams, D.; Coplon, N. and Coulson A.S. Lowaspartate transaminase activity in serum of patients undergoing chronic hemodialysis. Clin Chem . 2008. 18:567..
11. Olut, A.I. ; Ozsakarya, F.and Dilek, M. Seroprevalence ofhepatitis C virus infection and evaluation of serum aminotransferaselevels among haemodialysis patients in Izmir, Turkey. J Int. Med.Res.2005 ;33(6):641–6.
12. Trevizoli, J.E.; de Paula, ; Menezes, R. ; Ribeiro Velasco, L.F. ;
Amorim, R. ; de Carvalho, M.B. and Mendes L.S., et al. (). Hepatitis C is less aggressive in hemodialysis patients than in nonuremic patients. Clin. J. Am. Soc. Nephrol; 2008.3:1385-90
13. Fabrizi, F. ; Lunghi, G. ; Finazzi, S. ; Colucci, P. ; Pagano, A. andPonticelli, C. et al, Decreased serum aminotransferase activityin patients with chronic renal failure: impact on the detection of viral hepatitis. Am. J. Kidney Dis. ; 2001.38:1009–15.
14. Torres, P.U. Bone alkaline phosphatase isoforms in chronicrenal failure. Kidney Int.; 2002. 61:1178-9.
15.Regidor, D.L. ; Kovesdy, C.P. ; Mehrotra, R. ; Rambod, M. ;Jing, J.and McAllister C.J. et al. Serum alkaline phosphatase predictsmortality among maintenance hemodialysis patients. J. Am. Soc.Nephrol; 2004.19:2193-203.
16. Al-Wakeel J, Mailk GH, Al-Mohaya S, Mitwalli A, Baroudi F, El Gamal
H, et al. Liver disease in dialysis patients with antibodies to hepatitis C
virus. Nephrol Dial Transplant. 1996;11:2265-8.
17. Yuki N, Ishida H, Inoue T, Tabata T, Matsushita Y, Sasaki Y, et al.
Reappraisal of biochemical hepatitis C activity in hemodialysis patients.
J Clin Gastroenterol. 2000;30:187-94, http://dx.doi.org/10.1097/
00004836-200003000-00012.
18. lopes EP, Sette LH, Sette JB, Luna CF, Andrade AM, Moraes M, et al.
Serum alanine aminotransferase levels, hematocrit rate and body weight
correlations before and after hemodialysis session. Clinics (Sao Paulo).2009;64:941-5.
19.Trevizoli JE, Menezes R, Velasco LF, Amorim R, de Carvalho MB,
Mendes LS, et al. Hepatitis C is less aggressive in hemodialysis patients
than in nonuremic patients. Clin J Am Soc Nephrol. 2008;3:1385-90,
http://dx.doi.org/10.2215/CJN.01330308.
20. Cotler SJ, Diaz G, Gundlapalli S, Jakate S, Chawla A, Mital D, et al.
Characteristics of hepatitis C in renal transplant candidates. J Clin
Gastroenterol. 2002;35:191-5, http://dx.doi.org/10.1097/00004836-2002
08000-00013.
21. Ray L, Nanda SK, Chatterjee A, Sarangi R, Ganguly S.A comparative study of serum aminotransferases in chronic kidney diseasewith and without end-stage renal disease: Need for new reference ranges. Int J App Basic Med Res 2015;5:31-5.
References
1. Levey, A.S. ; Eckardt, K.U. and Tsukamoto, Y. ( 2005). Definition and classification of chronic kidney disease: a position statement from Kidney Disease:Improving Global Outcomes (KDIGO). Kidney Int.;67: 2089.
2. Abdelsamee E. M. Elamin,, Nagah A. A. Mohammed, Gad Allah Modawe. Aetiology of End-Stage Renal Disease among adult Sudanese patient. Sudan JMS Vol. 7, No.4. December 2012.
3. Elsharif ME, Elsharif EG. Causes of end-stagerenal disease in Sudan: A single centre experience.Saudi J Kidney Dis Transpl. 2011; 22: 373-376.
4. Musher Ismail Salih Kakey and Kamaran Kaiani Abdoulrahman. Estimation of Liver Parameters and Oxidative Stress in Chronic Renal Failure Patients on Hemodialysis in ErbilGovernorate. AIP Conference Proceedings 1888, 020029 (2017); https://doi.org/10.1063/1.5004306. Published Online: 21 September 2017.
5. Lomashvili, K.A., Garg, P., Narisawa, S., Millan, J.L. and O'Neill, W.C., Kidney international, 73 (9), 10241030(2008).
6. Fabrizi, F., Lunghi, G., Finazzi, S., Colucci, P., Pagano, A., Ponticelli, C. and Locatelli, F., American journal of kidney diseases, 38(5), 1009-1015 (2001).
7. Lopes, E.P., Sette, L.H.B., Sette, J.B.C., Luna, C.F., Andrade, A.M., Moraes, M., Sette, P.C., Menezes, R.,Cavalcanti, R.L. and Conceição, S.C., Clinics, 64 (10), 941-945 (2009).
8. Riyadh Hussein Wally. Effects of Chronic Kidney Disease on Some Liver Enzymes Activity before and After Dialysis. Journal of primary education.22 (96), 2016. 89-94.
9. Steel, R.G. and Torrie, J.H. Principle and procedure of statistics a biometrical approach1984.2nd., Mc.Graw-Hill,Inc.,Singapore.
10 . Wolf, P.L. ; Williams, D.; Coplon, N. and Coulson A.S. Lowaspartate transaminase activity in serum of patients undergoing chronic hemodialysis. Clin Chem . 2008. 18:567..
11. Olut, A.I. ; Ozsakarya, F.and Dilek, M. Seroprevalence ofhepatitis C virus infection and evaluation of serum aminotransferaselevels among haemodialysis patients in Izmir, Turkey. J Int. Med.Res.2005 ;33(6):641–6.
12. Trevizoli, J.E.; de Paula, ; Menezes, R. ; Ribeiro Velasco, L.F. ;
Amorim, R. ; de Carvalho, M.B. and Mendes L.S., et al. (). Hepatitis C is less aggressive in hemodialysis patients than in nonuremic patients. Clin. J. Am. Soc. Nephrol; 2008.3:1385-90
13. Fabrizi, F. ; Lunghi, G. ; Finazzi, S. ; Colucci, P. ; Pagano, A. andPonticelli, C. et al, Decreased serum aminotransferase activityin patients with chronic renal failure: impact on the detection of viral hepatitis. Am. J. Kidney Dis. ; 2001.38:1009–15.
14. Torres, P.U. Bone alkaline phosphatase isoforms in chronicrenal failure. Kidney Int.; 2002. 61:1178-9.
15.Regidor, D.L. ; Kovesdy, C.P. ; Mehrotra, R. ; Rambod, M. ;Jing, J.and McAllister C.J. et al. Serum alkaline phosphatase predictsmortality among maintenance hemodialysis patients. J. Am. Soc.Nephrol; 2004.19:2193-203.
16. Al-Wakeel J, Mailk GH, Al-Mohaya S, Mitwalli A, Baroudi F, El Gamal
H, et al. Liver disease in dialysis patients with antibodies to hepatitis C
virus. Nephrol Dial Transplant. 1996;11:2265-8.
17. Yuki N, Ishida H, Inoue T, Tabata T, Matsushita Y, Sasaki Y, et al.
Reappraisal of biochemical hepatitis C activity in hemodialysis patients.
J Clin Gastroenterol. 2000;30:187-94, http://dx.doi.org/10.1097/
00004836-200003000-00012.
18. lopes EP, Sette LH, Sette JB, Luna CF, Andrade AM, Moraes M, et al.
Serum alanine aminotransferase levels, hematocrit rate and body weight
correlations before and after hemodialysis session. Clinics (Sao Paulo).2009;64:941-5.
19.Trevizoli JE, Menezes R, Velasco LF, Amorim R, de Carvalho MB,
Mendes LS, et al. Hepatitis C is less aggressive in hemodialysis patients
than in nonuremic patients. Clin J Am Soc Nephrol. 2008;3:1385-90,
http://dx.doi.org/10.2215/CJN.01330308.
20. Cotler SJ, Diaz G, Gundlapalli S, Jakate S, Chawla A, Mital D, et al.
Characteristics of hepatitis C in renal transplant candidates. J Clin
Gastroenterol. 2002;35:191-5, http://dx.doi.org/10.1097/00004836-2002
08000-00013.
21. Ray L, Nanda SK, Chatterjee A, Sarangi R, Ganguly S.A comparative study of serum aminotransferases in chronic kidney diseasewith and without end-stage renal disease: Need for new reference ranges. Int J App Basic Med Res 2015;5:31-5.
References
1. Levey, A.S. ; Eckardt, K.U. and Tsukamoto, Y. ( 2005). Definition and classification of chronic kidney disease: a position statement from Kidney Disease:Improving Global Outcomes (KDIGO). Kidney Int.;67: 2089.
2. Abdelsamee E. M. Elamin,, Nagah A. A. Mohammed, Gad Allah Modawe. Aetiology of End-Stage Renal Disease among adult Sudanese patient. Sudan JMS Vol. 7, No.4. December 2012.
3. Elsharif ME, Elsharif EG. Causes of end-stagerenal disease in Sudan: A single centre experience.Saudi J Kidney Dis Transpl. 2011; 22: 373-376.
4. Musher Ismail Salih Kakey and Kamaran Kaiani Abdoulrahman. Estimation of Liver Parameters and Oxidative Stress in Chronic Renal Failure Patients on Hemodialysis in ErbilGovernorate. AIP Conference Proceedings 1888, 020029 (2017); https://doi.org/10.1063/1.5004306. Published Online: 21 September 2017.
5. Lomashvili, K.A., Garg, P., Narisawa, S., Millan, J.L. and O'Neill, W.C., Kidney international, 73 (9), 10241030(2008).
6. Fabrizi, F., Lunghi, G., Finazzi, S., Colucci, P., Pagano, A., Ponticelli, C. and Locatelli, F., American journal of kidney diseases, 38(5), 1009-1015 (2001).
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Published
2023-01-11
How to Cite
MODAWE, GadAllah Osamn et al.
Assessment of Serum Levels of Aminotransferse and Alkaline phosphatase Activity among Chronic Renal Failure with Hemodialysis.
Gezira Journal of Health Sciences, [S.l.], v. 17, n. 2, p. 31-38, jan. 2023.
ISSN 1810-5386. Available at: <http://journals.uofg.edu.sd/index.php/gjhs/article/view/1628>. Date accessed: 28 mar. 2023.
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